Resources to Promote Coordination and Collaboration across Deeply Phenotyped Longitudinal Behavioral and Social Studies of Aging (U24 Clinical Trial Not Allowed) | RFA AG 23 003

Opportunity Information: Apply for RFA AG 23 003

The National Institutes of Health (NIH) published this discretionary funding opportunity, RFA-AG-23-003, titled "Resources to Promote Coordination and Collaboration across Deeply Phenotyped Longitudinal Behavioral and Social Studies of Aging (U24 Clinical Trial Not Allowed)." It uses the cooperative agreement mechanism (U24), which means the awardee is expected to work in close partnership with NIH staff as substantial involvement is typical for this type of funding. The overall aim is not to run a clinical trial, but to build and operate a coordinated set of resources that make it easier for the research community to work across multiple long-running studies of aging that have unusually rich, detailed measurement ("deep phenotyping") in psychological, behavioral, social, and biobehavioral domains.

At the center of the FOA is the creation of a Resource Development Network. In practical terms, this network is meant to serve as shared infrastructure that helps separate longitudinal cohorts and studies align with one another, communicate, and collaborate more efficiently. These kinds of studies often collect overlapping but not identical measures over many years, which can make cross-study comparisons and pooled analyses difficult even when the scientific questions are similar. The NIH is looking for an effort that actively supports coordination across these studies so that investigators can more readily harmonize measures, compare findings, innovate on methods, and generate insights about aging that are stronger and more generalizable than any single study could deliver alone.

The opportunity is framed around studies of aging that are "deeply phenotyped" and "longitudinal," emphasizing repeated measurement over time and broad coverage of behavioral and social factors alongside psychological and biobehavioral content. That focus signals interest in the full complexity of aging as it unfolds in real life: behavior change, social context, stress and resilience, cognition and emotion, health behaviors, and biological correlates that connect lived experience to health outcomes. The infrastructure supported by this FOA is intended to make those complex datasets more interoperable and more useful for the field by promoting coordination and collaboration, and by enabling innovation in how these studies work together.

Eligibility is broad and includes many U.S.-based organizational types that commonly participate in NIH funding. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as listed); for-profit organizations other than small businesses; small businesses; and other organizations that meet NIH eligibility requirements. The FOA also explicitly notes additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, Indian/Native American Tribal Governments other than federally recognized, and U.S. territories or possessions.

Foreign eligibility is restricted in a way that is common for NIH opportunities focused on U.S. infrastructure. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as the applicant organization. Non-domestic components of U.S. organizations are also not eligible to apply. However, "foreign components" as defined in the NIH Grants Policy Statement are allowed, meaning a U.S. applicant may include certain well-justified activities performed outside the U.S. when permitted under NIH policy, even though the applicant institution itself must be domestic.

Administratively, the opportunity is categorized under the Health funding activity area and is associated with CFDA number 93.866. The original closing date listed is July 1, 2022, and the FOA creation date is December 20, 2021. The source information provided does not specify an award ceiling or the expected number of awards, so those details would normally be confirmed by reviewing the full FOA text and any related NIH notices. Overall, the grant is best understood as support for a coordinating, resource-building hub or network that strengthens the connective tissue across major longitudinal behavioral and social studies of aging, rather than funding a single hypothesis-driven study or any clinical trial activity.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Resources to Promote Coordination and Collaboration across Deeply Phenotyped Longitudinal Behavioral and Social Studies of Aging (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
• This funding opportunity was created on 2021-12-20.
• Applicants must submit their applications by 2022-07-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AG 23 003

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